Through games of Feb. 28, 2010:
| # | Team | W-L | Pts. | Last Week |
| 1 | Amherst (21) | 27-0 | 617 | 1 |
| 2 | Kean (3) | 26-1 | 595 | 2 |
| 3 | Illinois Wesleyan (1) | 26-1 | 571 | 3 |
| 4 | Hope | 27-1 | 554 | 4 |
| 5 | George Fox | 25-2 | 516 | 5 |
| 6 | Washington U. | 23-2 | 502 | 6 |
| 7 | Marymount | 26-1 | 471 | 7 |
| 8 | Moravian | 25-2 | 442 | 9 |
| 9 | William Paterson | 25-2 | 416 | 8 |
| 10 | Christopher Newport | 28-0 | 400 | 12 |
| 11 | DePauw | 25-3 | 337 | 14 |
| 12 | Calvin | 24-4 | 321 | 11 |
| 13 | Thomas More | 25-3 | 306 | 16 |
| 14 | Carthage | 22-4 | 289 | 10 |
| 15 | Puget Sound | 23-4 | 275 | 13 |
| 16 | Louisiana College | 24-2 | 264 | 17 |
| 17 | Messiah | 23-4 | 221 | 20 |
| 18 | Scranton | 22-5 | 166 | 15 |
| 19 | Lebanon Valley | 23-4 | 108 | 19 |
| 20 | Colby | 23-4 | 99 | 23 |
| 21 | Farmingdale State | 25-1 | 91 | — |
| 22 | Chicago | 19-6 | 86 | 21 |
| 23 | UW-Stevens Point | 21-6 | 73 | — |
| 24 | Washington and Jefferson | 23-4 | 65 | 18 |
| 25 | St. Norbert | 22-3 | 57 | — |
Dropped out: No. 22 Muhlenberg; No. 24 Mary Washington; No. 25 Tufts.
Others receiving votes: Tufts 53, Mount Union 52, Mary Washington 41, Bowdoin 39, Muhlenberg 30, Rochester 18, Gettysburg 17, UW-Whitewater 14, McDaniel 12, Ithaca 5, Cortland State 1, Hendrix 1.
The D3hoops.com Top 25 is voted on by a panel of 25 coaches, Sports Information Directors and media members from across the country, and is published weekly.